Hemophilia: An Overview for the Home Infusion Clinician - INFUSION Article

Hemophilia is a hereditary bleeding disorder where blood fails to clot properly due to a deficiency or absence of clotting factors. Management typically involves the infusion of clotting factor proteins to control and prevent bleeding episodes, whether from injuries or during planned medical procedures. While most hemophilia care is overseen by federal Hemophilia Treatment Centers, home infusion pharmacies also play a critical role in treatment. This educational activity will explore the essential components of hemophilia management, including an overview of the coagulation cascade, the differences between Hemophilia A and B, and the available treatment options. The discussion will also address important safety concerns related to plasma pooling in the production of clotting factors and blood products, as well as the unique challenges of home-based care. This activity is designed for pharmacists, pharmacy technicians, and nurses.

Learning Objectives:

  1. Describe the mechanism of the clotting cascade.
  2. Differentiate between hemophilia A and B.
  3. Differentiate between hemophilia treatments and their indications. 
  4. List 3 considerations for clinicians when caring for hemophilia patients with chronic co-infections such as HIV/AIDS and Hepatitis C.

NHIA General CE Information

Vy Karp (Dang)

PharmD

Optum Infusion Services

Vy Karp (Dang), Pharm.D, HDDP is an Infusion Clinical Pharmacist at Optum Infusion Services in Wallingfor, Connecticut. She earned a Bachelor’s degree in Health Sciences at University of California, Irvine and a Doctor of Pharmacy degree at Roseman University of Health Sciences College of Pharmacy. Karp was a pharmacy practice resident in Las Vegas. She has practiced in infectious disease, genetics, oncology, and emergency medicine. Her current practice focuses on parenteral nutrition, acute care, inotropes, IV anti-infective agents, and pain management. She also provides clinical care for high-cost IV drugs including immunoglobulins (IGs), enzyme replacement therapies (eg. Fabrazyme), Radicava, Solaris, Entyvio, biologics, and alpha-1 proteinase inhibitors (eg. Glassia, Zemaira). Dang is currently licensed in Arizona, Connecticut, Massachusetts, Nevada and Ohio.

NHIA Requires planners, faculty, and others who affect the content of this activity to disclose all financial relationships they have with ineligible companies. All relevant financial relationships are thoroughly vetted and mitigated according to policy. 

Vy Karp (Dang) has no relevant financial relationships with ineligible companies to disclose.

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Congenital Homophilia A: Overview, Home Management, and a Case Study
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8 Questions Hemophilia: An Overview for the Home Infusion Clinician INFUSION Article 1.0 CE JA4008389-0000-25-036-H01-P&T & 202901174-RN&RD
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